Physician. Son of Malcolm Macleod (1695-1761), 10th of Raasay, and Mary Mackenzie, a daughter of Alexander Mackenzie of Applecross. Brother of John MacLeod, 11th of Raasay. Married to Anne Macdonald, a daughter of Alexander Macdonald of Boisdale, with whom he had several children.
He fought on the Jacobite side during the uprising in 1745-46 together with his father, and his cousin Malcolm Macleod.
Boswell and Dr Johnson met Dr MacLeod on Raasay after their arrival on that island on September 8, 1773. Boswell described him as a "sensible, civil man, [who] I am told has good skill." Boswell further wrote that Macleod had had bad health for some years and had given over his practice.
In the afternoon of September 12, 1773, and back on Skye, Johnson and Boswell rode from Portree to Macleod's house at Eyre, where they had a comfortable dish of tea and met the Doctor's wife and brother. After this, the Doctor rode with them a mile further on to the house of Allan MacDonald, tacksman of Kingsburgh, and his wife, the celebrated Flora MacDonald.